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Some things are far easier to watch than to read about. These explainers cover the concepts students get stuck on — how sequencing actually works, why we run FastQC, how a read finds its place in the genome, and how a neural network learns.
Sequencing
Watch a single DNA fragment get read base by base: fluorescent nucleotides bind, the camera fires, and the light pattern becomes letters.
Sequencing
Coverage is an average, and averages hide their distribution. Move the slider from 1x to 100x and watch the callable fraction, the detection power and the cost each respond very differently.
Sequencing
Eight molecules go into a PCR and forty reads come out. Watch three ways of counting them disagree, and see why a barcode attached before amplification is the only one that gets the right answer.